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1

Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy

Masayoshi Hioki, Shunsuke Kagawa, Toshiya Fujiwara, Ryo Sakai, Toru Kojima, Yuichi Watanabe, Yuuri Hashimoto, Futoshi Uno, Noriaki Tanaka, Toshiyoshi Fujiwara

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

2

Influence of the Angle between the Nasal Cavity Axis and Nosepiece in Acoustic Rhinometry.

KASE, YASUHIRO, TANAKA, TOSHIYOSHI, MIZUNO, MASAHIRO, ICHIMURA, KEIICH, IINUMA, TOSHITAKA

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1994

Language:

english

File:

PDF, 2.19 MB

english, 1994

3

10.1271/nogeikagaku1924.76.385

FUJIWARA, Toshiyoshi, TANAKA, Noriaki

Journal:

Journal of the agricultural chemical society of Japan

Year:

2002

File:

PDF, 302 KB

2002

4

Insertion of a Suicide Gene into an Immortalized Human Hepatocyte Cell Line

Kobayashi, Naoya, Noguchi, Hirofumi, Totsugawa, Toshinori, Watanabe, Takamasa, Matsumura, Toshihisa, Fujiwara, Toshiyoshi, Miyazaki, Masahiro, Fukaya, Kenichi, Namba, Masayoshi, Tanaka, Noriaki

Journal:

Cell Transplantation

Year:

2001

File:

PDF, 299 KB

2001

5

Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

Katsuda, Koh, Kataoka, Masafumi, Uno, Futoshi, Murakami, Takayoshi, Kondo, Tadashi, Roth, Jack A, Tanaka, Noriaki, Fujiwara, Toshiyoshi

Journal:

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

6

143. Development of Telomerase Specific Antineoplastic Adenovirus Telomelysin (OBP-301): Establishment of Useful Assay and Assessment for Antitumor Activity

Hashimoto, Yuuri, Teraishi, Fuminori, Watanabe, Yuichi, Kagawa, Shunsuke, Kawamura, Hitoshi, Nagai, Katsuyuki, Tanaka, Noriaki, Urata, Yasuo, Fujiwara, Toshiyoshi

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

7

Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells

Kazuhiro Tanaka, Takashi Sasayama, Katsu Mizukawa, Atsufumi Kawamura, Takeshi Kondoh, Kohkichi Hosoda, Toshiyoshi Fujiwara, Eiji Kohmura

Journal:

Journal of Neuro-Oncology

Year:

2007

Language:

english

File:

PDF, 573 KB

english, 2007

8

Overexpression of the p21 sdi1 gene induces senescence-like state in human cancer cells: implication for senescence-directed molecular therapy for cancer

Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Kadowaki, Yoshihiko, Fukazawa, Takuya, Sok-Joo, Rha, Roth, Jack A, Tanaka, Noriaki

Journal:

Cell Death & Differentiation

Year:

1999

Language:

english

File:

PDF, 1.23 MB

english, 1999

9

Esophageal Intramural Pseudodiverticulosis With Esophageal Strictures Successfully Treated With Dilation Therapy

Fuminori Teraishi, Toshiyoshi Fujiwara, Atsushi Jikuhara, Shingo Kamitani, Yasuo Morino, Katsuaki Sato, Noriaki Tanaka

Journal:

The Annals of Thoracic Surgery

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

10

303. Enhanced Antitumor Efficacy of Telomerase-Selective Oncolytic Adenoviral Agent OBP-401 with Docetaxel: Preclinical Evaluation of Chemovirotherapy

Ikeda, Yoshihiro, Fujiwara, Toshiya, Kagawa, Shunsuke, Hioki, Masayoshi, Sakai, Ryo, Kojima, Toru, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 93 KB

english, 2006

11

SPIE Proceedings [SPIE SPIE Asia-Pacific Remote Sensing - New Delhi, India (Monday 4 April 2016)] Earth Observing Missions and Sensors: Development, Implementation, and Characterization IV - Early test results of proto-flight test of Second Generation Global Imager (SGLI) Infrared Scanning Radiometer (IRS)

Xiong, Xiaoxiong J., Kuriakose, Saji A., Kimura, Toshiyoshi, Tanaka, Kazuhiro, Amano, Takahiro, Uchikata, Tatsuya, Sakashita, Takashi

Year:

2016

Language:

english

File:

PDF, 341 KB

english, 2016

12

The effect of endothelin on neurotransmitted regulation of vascular tension in the nasal mucosa.

OKITA, WATARU, ICHIMURA, KEIICHI, TANAKA, TOSHIYOSHI, IINUMA, TOSHITAKA

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1992

File:

PDF, 493 KB

1992

13

Efficient Cre/loxP Site-Specific Recombination in a HepG2 Human Liver Cell Line

Kobayashi, Naoya, Noguchi, Hirofumi, Westerman, Karen A., Matsumura, Toshihisa, Watanabe, Takamasa, Totsugawa, Toshinori, Fujiwara, Toshiyoshi, Leboulch, Philippe, Tanaka, Noriaki

Journal:

Cell Transplantation

Year:

2000

Language:

english

File:

PDF, 3.10 MB

english, 2000

14

Telomerase-Specific Oncolytic Virotherapy for Human Cancer with the hTERT Promoter

FUJIWARA, Toshiyoshi, TANAKA, Noriaki

Journal:

Year:

2008

File:

PDF, 398 KB

2008

15

Genomic characterization of closely related species in the Rumoiensis clade infers ecogenomic signatures to nonâmarine environments

Tanaka, Mami, Kumakura, Daiki, Mino, Sayaka, Doi, Hidetaka, Ogura, Yoshitoshi, Hayashi, Tetsuya, Yumoto, Isao, Cai, Man, Zhou, YuâGuang, GomezâGil, Bruno, Araki, Toshiyoshi, Sawabe, Tomoo

Journal:

Environmental Microbiology

Year:

2020

File:

PDF, 1.43 MB

2020

16

Immunological evaluation of personalized peptide vaccination in combination with a 5-fluorouracil derivative (TS-1) for advanced gastric or colorectal carcinoma patients

Yuji Sato, Toshiyoshi Fujiwara, Takashi Mine, Hiroki Shomura, Shigenori Homma, Yoshiaki Maeda, Naoyuki Tokunaga, Yoshihiro Ikeda, Yuki Ishihara, Akira Yamada, Noriaki Tanaka, Kyogo Itoh, Mamoru Harada

Journal:

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

17

310. Antitumor Effect of Telomerase-Specific Virotherapy in Pleural Dissemination of Human Malignant Mesothelioma

Watanabe, Yuichi, Hashimoto, Yuuri, Kojima, Toru, Kagawa, Shunsuke, Kawamura, Hitoshi, Nagai, Katsuyuki, Tanaka, Noriaki, Urata, Yasuo, Fujiwara, Toshiyoshi

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 84 KB

english, 2006

18

1004. c-Jun NH2-Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in Adenovirus-Mediated Transgene Expression

Teraishi, Fuminori, Fang, Bingliang, Liu, Annin, Uno, Futoshi, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Tanaka, Noriaki

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 90 KB

english, 2006

19

Ectopic p21sdi1 gene transfer induces retinoic acid receptor β expression and sensitizes human cancer cells to retinoid treatment

Fuminori Teraishi, Yoshihiko Kadowaki, Yasuhisa Tango, Takeshi Kawashima, Tatsuo Umeoka, Shunsuke Kagawa, Noriaki Tanaka, Toshiyoshi Fujiwara

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 590 KB

english, 2003

20

Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: Preclinical evaluation of chemovirotherapy

Toshiya Fujiwara, Shunsuke Kagawa, Hiroyuki Kishimoto, Yoshikatsu Endo, Masayoshi Hioki, Yoshihiro Ikeda, Ryo Sakai, Yasuo Urata, Noriaki Tanaka, Toshiyoshi Fujiwara

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 1.41 MB

english, 2006

21

Heparanase Expression Correlates with Invasion and Poor Prognosis in Gastric Cancers

Takaoka, Munenori, Naomoto, Yoshio, Ohkawa, Takaomi, Uetsuka, Hirokazu, Shirakawa, Yasuhiro, Uno, Futoshi, Fujiwara, Toshiyoshi, Gunduz, Mehmet, Nagatsuka, Hitoshi, Nakajima, Motowo, Tanaka, Noriaki,

Journal:

Laboratory Investigation

Year:

2003

Language:

english

File:

PDF, 3.25 MB

english, 2003

22

SPIE Proceedings [SPIE Remote Sensing - Stockholm, Sweden (Monday 11 September 2006)] Sensors, Systems, and Next-Generation Satellites X - Status of the GCOM-W and onboard AMSR follow-on instrument

Imaoka, Keiji, Meynart, Roland, Neeck, Steven P., Shibata, Akira, Kachi, Misako, Shimoda, Haruhisa, Kasahara, Marehito, Iida, Yukiei, Tanaka, Kazuhiro, Kimura, Toshiyoshi, Tange, Yoshio, Shimoda, Haru

Year:

2006

Language:

english

File:

PDF, 690 KB

english, 2006

23

EVIDENCE FOR THE PRESENCE OF ENDOTHELIUM-DERIVED RELAXING FACTOR IN NASAL BLOOD VESSELS

OKITA, WATARU, TANAKA, TOSHIYOSHI, IINUMA, TOSHITAKA, ICHIMURA, KEIICHI

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1993

File:

PDF, 1.48 MB

1993

24

Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study

Suzuki, Nobuaki, Hazama, Shoichi, Iguchi, Haruo, Uesugi, Kazuhiro, Tanaka, Hiroaki, Hirakawa, Kosei, Aruga, Atsushi, Hatori, Takashi, Ishizaki, Hidenobu, Umeda, Yuzo, Fujiwara, Toshiyoshi, Ikemoto, Te

Journal:

Year:

2017

Language:

english

File:

PDF, 613 KB

english, 2017

25

p53 expression overcomes p21-WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells

Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hizuta, Akio, Yasuda, Tatsuji, Zhang, Wei-Wei, Roth, Jack A, Tanaka, Noriaki

Journal:

Year:

1997

Language:

english

File:

PDF, 430 KB

english, 1997

26

Combination of Tumor Necrosis Factor Alpha and Interferon Alpha Induces Apoptotic Cell Death through a c-myc–Dependent Pathway in p53 Mutant H226br Non–Small-Cell Lung Cancer Cell Line

Yasuo Yasuoka, Yoshio Naomoto, Tomoki Yamatsuji, Munenori Takaoka, Masashi Kimura, Hirokazu Uetsuka, Nagahide Matsubara, Toshiyoshi Fujiwara, Mehmet Gunduz, Noriaki Tanaka, Minoru Haisa

Journal:

Experimental Cell Research

Year:

2001

Language:

english

File:

PDF, 377 KB

english, 2001

27

Cre/loxP-Based Reversible Immortalization of Human Hepatocytes

Kobayashi, Naoya, Noguchi, Hirofumi, Westerman, Karen A., Watanabe, Takamasa, Matsumura, Toshihisa, Totsugawa, Toshinori, Fujiwara, Toshiyoshi, Leboulch, Philippe, Tanaka, Noriaki

Journal:

Cell Transplantation

Year:

2001

File:

PDF, 123 KB

2001

28

In vivo influence of p53 status on proliferation and chemoradiosensitivity in non-small-cell lung cancer

Jose Antonio Perdomo, Yoshio Naomoto, Minoru Haisa, Toshiyoshi Fujiwara, Madoka Hamada, Yasuo Yasuoka, Noriaki Tanaka

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1998

Language:

english

File:

PDF, 1.23 MB

english, 1998

29

Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells

Takanori Watanabe, Masayoshi Hioki, Toshiya Fujiwara, Masahiko Nishizaki, Shunsuke Kagawa, Masaki Taki, Hiroyuki Kishimoto, Yoshikatsu Endo, Yasuo Urata, Noriaki Tanaka, Toshiyoshi Fujiwara

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 568 KB

english, 2006

30

639. In Vivo Imaging of Lymph Node Metastasis with Telomerase-Specific Replication-Competent Adenovirus Containing Green Fluorescent Protein Gene

Kojima, Toru, Kishimoto, Hiroyuki, Watanabe, Yuichi, Kagawa, Shunsuke, Teraishi, Fuminori, Hioki, Masayoshi, Ikeda, Yoshihiro, Sakai, Ryo, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi

Journal:

Molecular Therapy

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

31

Adenomyoma of the stomach presenting as localized peritonitis

Shunsuke Kagawa, Toshiyoshi Fujiwara, Masahiko Nishizaki, Yoshio Naomoto, Isozaki Hiroshi, Noriaki Tanaka

Journal:

Digestive Diseases and Sciences

Year:

2007

Language:

english

File:

PDF, 234 KB

english, 2007

32

SPIE Proceedings [SPIE Remote Sensing - Maspalomas, Canary Islands, Spain (Monday 13 September 2004)] Sensors, Systems, and Next-Generation Satellites VIII - Concept study of multispectral imager for next generation

Kimura, Toshiyoshi, Meynart, Roland, Neeck, Steven P., Tange, Yoshio, Tanaka, Kazuhiro, Shimoda, Haruhisa, Itoh, Nobunari, Matsuyama, Hiroko, Okamura, Yoshihiko, Kasahara, Marehito, Honda, Yoshiaki

Year:

2004

Language:

english

File:

PDF, 391 KB

english, 2004

33

Postirradiation Ethmoid Sinus Sarcoma with Intracranial Extention; A Case Report.

TAKEGOSHI, Hideki, NIBU, Ken-ichi, TANAKA, Tadashi, TANAKA, Toshiyoshi, ICHIMURA, Keiichi

Journal:

Practica Oto-Rhino-Laryngologica

Year:

1995

Language:

english

File:

PDF, 4.45 MB

english, 1995

34

The Effect of Unilateral Nasal Patency on the Contralateral Side .

KASE, YASUHIRO, TANAKA, TOSHIYOSHI, IINUMA, TOSHITAKA

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

35

Overexpression of the wild-type p53 gene inhibits NF-κB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

Shao, Jianghua, Fujiwara, Toshiyoshi, Kadowaki, Yoshihiko, Fukazawa, Takuya, Waku, Toshihiko, Itoshima, Takahiro, Yamatsuji, Tomoki, Nishizaki, Masahiko, Roth, Jack A, Tanaka, Noriaki

Journal:

Year:

2000

Language:

english

File:

PDF, 631 KB

english, 2000

36

Adenovirus-Mediated p14 ARF Gene Transfer Cooperates with Ad5CMV-p53 to Induce Apoptosis in Human Cancer Cells

Tango, Yasuhisa, Fujiwara, Toshiyoshi, Itoshima, Takahiro, Takata, Yoshiko, Katsuda, Kou, Uno, Futoshi, Ohtani, Shoichiro, Tani, Tohru, Roth, Jack A., Tanaka, Noriaki

Journal:

Human Gene Therapy

Year:

2002

Language:

english

File:

PDF, 406 KB

english, 2002

37

P1-154: Antitumor effect of Telomerase-Selective Oncolytic Adenoviral Agent OBP-301 (Telomelysin) in pleural dissemination of human malignant mesothelioma

Kagawa, Shunsuke, Watanabe, Yuichi, Hashimoto, Yuuri, Kojima, Toru, Uno, Futoshi, Kuroda, Shinji, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi

Journal:

Journal of Thoracic Oncology

Year:

2007

Language:

english

File:

PDF, 173 KB

english, 2007

38

Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent

Nobuyuki Ogawa, Toshiyoshi Fujiwara, Shunsuke Kagawa, Masahiko Nishizaki, Yoshinori Morimoto, Tohru Tanida, Akio Hizuta, Tatsuji Yasuda, Jack A. Roth, Noriaki Tanaka

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 666 KB

english, 1997

39

Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells

Toshiaki Ohara, Munenori Takaoka, Shinichi Toyooka, Yasuko Tomono, Toshio Nishikawa, Yasuhiro Shirakawa, Tomoki Yamatsuji, Noriaki Tanaka, Toshiyoshi Fujiwara, Yoshio Naomoto

Journal:

Year:

2011

Language:

english

File:

PDF, 401 KB

english, 2011

40

Appendiceal mucocele with concomitant colonic cancer

Toshiyoshi Fujiwara, Akio Hizuta, Hiromi Iwagaki, Tsuyoshi Matsuno, Madoka Hamada, Noriaki Tanaka, Kunzo Orita

Journal:

Diseases of the Colon & Rectum

Year:

1996

Language:

english

File:

PDF, 1.71 MB

english, 1996

41

p53 Inhibits Adriamycin-Induced Down-Regulation of Cyclin D1 Expression in Human Cancer Cells

Jianghua Shao, Fuminori Teraishi, Koh Katsuda, Noriaki Tanaka, Toshiyoshi Fujiwara

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 302 KB

english, 2002

42

Cloning and Characterization of a β-1,4-Mannanase 5C Possessing a Family 27 Carbohydrate-Binding Module from a Marine Bacterium, Vibrio sp. Strain MA-138

TANAKA, Megumi, UMEMOTO, Yoshiaki, OKAMURA, Hidenori, NAKANO, Daiichirou, TAMARU, Yutaka, ARAKI, Toshiyoshi

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

43

SPIE Proceedings [SPIE Remote Sensing - Bruges, Belgium (Monday 19 September 2005)] Sensors, Systems, and Next-Generation Satellites IX - A concept study for Japanese climate change observation mission: GCOM-C

Kimura, Toshiyoshi, Meynart, Roland, Neeck, Steven P., Tanaka, Kazuhiro, Okamura, Yoshihiko, Shimoda, Haruhisa, Fukui, Shigemitsu, Matsuura, Naoto, Tange, Yoshio, Honda, Yoshiaki, Shimoda, Haruhisa

Year:

2005

Language:

english

File:

PDF, 613 KB

english, 2005

44

Adenovirus-Mediated p53 Gene Therapy for Human Cancer

Fujiwara, Toshiyoshi, Kataoka, Masafumi, Tanaka, Noriaki

Journal:

Molecular Urology

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

45

SPIE Proceedings [SPIE Optical Science and Technology, SPIE's 48th Annual Meeting - San Diego, CA (Sunday 3 August 2003)] Earth Observing Systems VIII - First results from GLI"s solar calibration

Nieke, Jens, Tanaka, Kazuhiro, Itoh, Nobunari, Kimura, Toshiyoshi, Kurihara, Shigehisa, Barnes, William L.

Year:

2003

Language:

english

File:

PDF, 818 KB

english, 2003

46

The vasoactivity of endothelin in the nasal mucosa.

OKITA, WATARU, ICHIMURA, KEIICHI, TANAKA, TOSHIYOSHI, IINUMA, TOSHITAKA

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1991

File:

PDF, 2.95 MB

1991

47

Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 (‘Telomelysin-RGD’)

Taki, Masaki, Kagawa, Shunsuke, Nishizaki, Masahiko, Mizuguchi, Hiroyuki, Hayakawa, Takao, Kyo, Satoru, Nagai, Katsuyuki, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi

Journal:

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

48

The Ethmoido-Maxillary Plate and Paranasal Sinuses. A Study by HRCT.

IINUMA, TOSHITAKA, SIGA, HIDETAKE, KASE, YASUHIRO, TANAKA, TOSHIYOSHI, OKITA, WATARU, KURIYAMA, JUN-ICHI

Journal:

Nippon Jibiinkoka Gakkai Kaiho

Year:

1994

File:

PDF, 1022 KB

1994

49

SPIE Proceedings [SPIE SPIE Remote Sensing - Edinburgh, United Kingdom (Monday 26 September 2016)] Sensors, Systems, and Next-Generation Satellites XX - Radiometric performance of Second-generation Global Imager (SGLI) using integrating spheres

Meynart, Roland, Neeck, Steven P., Kimura, Toshiyoshi, Shimoda, Haruhisa, Hashiguchi, Taichiro, Okamura, Yoshihiko, Tanaka, Kazuhiro, Nakajima, Yukinori, Suzuki, Koichi, Sakashita, Takashi, Amano, Tak

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

50

SPIE Proceedings [SPIE Remote Sensing - Bruges, Belgium (Monday 19 September 2005)] Sensors, Systems, and Next-Generation Satellites IX - Overview of the GCOM-W mission and AMSR follow-on instrument

Imaoka, Keiji, Meynart, Roland, Neeck, Steven P., Shibata, Akira, Ebuchi, Naoto, Shimoda, Haruhisa, Igarashi, Tamotsu, Fukui, Shigemitsu, Tanaka, Kazuhiro, Kimura, Toshiyoshi, Sezai, Toshihiro, Tange,

Year:

2005

Language:

english

File:

PDF, 474 KB

english, 2005

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